SKAMPI (Sichtbare KAtheter im MPI zur schonenden Behandlung multimorbider Patienten)

Magnetic Particle Imaging (MPI) allows to image the spatial distribution of superparamagnetic iron oxide nanoparticles (SPION). Since MPI combines a high sensitivity with good spatial and temporal resolution it is a promising technique for cardiovascular interventions. Therefore, it is necessary to visualize the used instruments. One possibility is to coat them with suitable SPION varnish.

Within the project a suitable coatings for different medical instruments should be identified. The aim is to develop a coating that is safe to use and will not influence the mechanical characteristics of the instruments. Further, a suitable visualization will be developed with focus on the signal separation of instrument and a SPION filled vessel.

 

SPION coated wire. Images taken from Haegele et al. (DOI: 10.1088/0031-9155/61/16/N415)

Grants

  • Federal Ministry of Education and Research under grant number BMBF 13GW0071D /li>

Cooperations

  • Evonik Industries
  • Osypka

Publications

2021[ to top ]
  • Wegner, F., von Gladiss, A., Haegele, J., Grzyska, U., Sieren, M. M., Stahlberg, E., Oechtering, T. H., Lüdtke-Buzug, K., Barkhausen, J., Buzug, T. M. and Friedrich, T.: Magnetic Particle Imaging: In vitro Signal Analysis and Lumen Quantification of 21 Endovascular Stents, International Journal of Nanomedicine, 16, 213–221, 2021, DOI: 10.2147/IJN.S284694.
2020[ to top ]
  • Wegner, F., Friedrich, T., von Gladiss, A., Grzyska, U., Sieren, M. M., Lüdtke-Buzug, K., Frydrychowicz, A., Buzug, T. M., Barkhausen, J. and Haegele, J.: Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study, CardioVascular and Interventional Radiology, 43(2), 331–338, 2020, DOI: 10.1007/s00270-019-02347-x.
2018[ to top ]
  • Wegner, F., Friedrich, T., Panagiotopoulos, N., Valmaa, S., Goltz, J. P., Vogt, F. M., Koch, M. A., Buzug, T. M., Barkhausen, J. and Haegele, J.: First heating measurements of endovascular stents in magnetic particle imaging, Physics in Medicine and Biology, 63(4), 045005, 2018, DOI: 10.1088%2F1361-6560%2Faaa79c.